Acute Myeloid Leukemia Presenting as Myeloid Sarcoma with aPredisposition to the Gynecologic Tract

Myeloid sarcoma (MS) is a rare, extramedullary tumor consisting of immature white blood cells of myeloid lineage. MS is usuallyassociated with the concurrent diagnosis of acute myeloid leukemia (AML) but can also present in the absence of bone marrowdisease or at relapse of AML. MS of the gynecologic tract is exceedingly rare; however, it is hypothesized that it is likely moreprevalent than previously understood given postmortemfindings and persistence in preserved ovarian tissue. There is minimalliterature surrounding MS and extramedullary relapse with no clear guidelines. This is a case report of a 48-year-old womanwith MS involving the uterine corpus, fallopian tubes, and left ovary followed by a literature review. The overall aim is to reviewdata regarding leukemic immune evasion and sanctuary sites in order to raise awareness as this represents an important andunderrecognized hematologic malignancy in an often misdiagnosed, underrecognized site.