Title of article :
Signet Ring Cell Carcinoma of the Colon in Young Adults: A CaseReport and Literature Review
Author/Authors :
Farraj, Farida Abi Faculty of Medicine - American University of Beirut - Beirut, Lebanon , Sabbagh, Hadi Faculty of Medicine - American University of Beirut - Beirut, Lebanon , Aridi, Tarek Faculty of Medicine - American University of Beirut - Beirut, Lebanon , Fakhruddin, Najla Department of Pathology - Hammoud Hospital University Medical Center - Saida, Lebanon , Farhat, Fadi Department of Oncology - Hammoud Hospital University Medical Center - Saida, Lebanon
Abstract :
Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to itsdiagnosis and management. The incidence of CRC in the adolescent and young adult (AYA) population has increased over thepast couple of decades despite the decline in the overall occurrence of CRC in the general population. Signet ring cell carcinomais one of the rare histopathologic subtypes of CRC; however, it is more prevalent in AYA patients than in older adults andpresents with unconventional histologic characteristics, a distinct clinical behavior, and a poor prognosis. We report a case of aprimary signet ring cell adenocarcinoma of the ascending colon in a 19-year-old male who presented with unusual signs andsymptoms and was diagnosed with stage IVA (T4a N0 M1, with peritoneal seeding). The unusual presentation and location ofthe tumor in this case warrant further investigation
Keywords :
Signet Ring Cell Carcinoma , Colon , Young Adults , AYA , Colorectal cancer (CRC)
Journal title :
Case Reports in Oncological Medicine
