Author/Authors :
Nagase, Takahide Department of Respiratory Medicine - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Sakatani, Toshio Department of Respiratory Medicine - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Kage, Hidenori Department of Respiratory Medicine - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Watanabe, Kaoru Department of Respiratory Medicine - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Hiraishi, Yoshihisa Department of Respiratory Medicine - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Takayanagi, Shunsaku Department of Neurosurgery - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Tanaka,Shota Department of Neurosurgery - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Saito, Nobuhito Department of Neurosurgery - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Shinozaki-Ushiku, Aya Department of Pathology - Graduate School of Medicine - University of Tokyo - Tokyo, Japan , Ushiku, Tetsuo Department of Pathology - Graduate School of Medicine - University of Tokyo - Tokyo, Japan
Abstract :
Brain metastasis frequently develops in non-small-cell lung cancer (NSCLC). Here, we report a patient who developed brainmetastasis fromALK-positive NSCLC which mimicked brain abscess. He was admitted for suspected obstructive pneumonianine months after curative lung resection. Head magnetic resonance imaging revealed a cavitary lesion, which was compatiblewith brain abscess but rare in brain metastasis. However, after treatment with antibiotics, the brain lesion increased in size.Aspiration of the liquid content of the brain lesion revealed cancer cells. When a brain lesion suggestive of abscess develops in apatient withALK-positive NSCLC, aspiration may be necessary to differentiate metastasis from abscess.
Keywords :
Brain Metastasis Mimicking Brain Abscess , ALK-Positive Non-Small-Cell , Lung Cancer , NSCLC
