Title of article :
Choriocarcinoma Syndrome: A Potentially Fatal Complication ofTesticular Cancer
Author/Authors :
Zeitjian, Vicken Sarkis Creighton University Arizona Health Education Alliance - Department of Internal Medicine - USA , Arslan, Waqas Creighton University Arizona Health Education Alliance - Department of Hematology and Oncology, USA , Amar, Surabhi Creighton University Arizona Health Education Alliance - Department of Hematology and Oncology, USA , Borja-Alvarez, Andres Creighton University Arizona Health Education Alliance - Department of Pulmonary and Critical Care, USA
Abstract :
Choriocarcinoma syndrome is a rare clinical entity with advanced, high volume choriocarcinomatous tumors and markedlyelevated B-hCG (>50,000 IU/L). Recognition is important because the diagnosis of this syndrome identifies poor prognosiswithout mortality-proven management options. We present a case of a male in his twenties with metastatic choriocarcinomawho developed choriocarcinoma syndrome acutely after chemotherapy commencement. The patient deceased after hypoxicrespiratory failure due to diffuse alveolar hemorrhage as a result of death of vascular tumors. While the prognosis for earlydiagnosis and treatment is excellent, the prognosis for late diagnosis is grim. Unfortunately, despite surgical or chemotherapeuticintervention, this syndrome has poor outcome
Keywords :
Choriocarcinoma Syndrome , Potentially Fatal Complication , Testicular Cancer , GCTs
Journal title :
Case Reports in Oncological Medicine
