Author/Authors :
Mostafavi, Nasser Infectious Diseases and Tropical Medicine Research Center - Isfahan Universitya of Medical Sciences, Isfahan, Iran , Rostami, Soodabeh Nosocomial Infection Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Ataei, Behrooz Infectious Diseases and Tropical Medicine Research Center - Isfahan Universitya of Medical Sciences, Isfahan, Iran , Mobasherizadeh, Sina Nosocomial Infection Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Cheraghi, Azam Department of Hospitals Supervision and Accreditation - Vice-Chancellery for Clinical Affairs - Isfahan University of Medical Sciences, Isfahan, Iran , Nouri, Samereh Department of Microbiology - Clinical Laboratory of Alzahra Medical Center, Isfahan, Iran , Pourdad, Arezoo Alzahra Medical Center - Isfahan University of Medical Sciences, Isfahan, Iran , Ataabadi, Parisa Alzahra Medical Center - Isfahan University of Medical Sciences, Isfahan, Iran , Almasi, Naser Department of Microbiology - Clinical Laboratory of Dr. Shariati Hospital - Isfahan Social Security Organization, Isfahan, Iran , Heidary, Leila Department of Microbiology - Clinical Laboratory of Dr. Shariati Hospital - Isfahan Social Security Organization, Isfahan, Iran , Naderi, Kourosh Department of Microbiology - Clinical Laboratory of Dr. Shariati Hospital - Isfahan Social Security Organization, Isfahan, Iran , Korangbeheshti, Setareh Department of Microbiology - Clinical Laboratory of Dr. Shariati Hospital - Isfahan Social Security Organization, Isfahan, Iran , Navabi, Shiva Department of Microbiology - Clinical Laboratory of Dr. Gharazi Hospital - Isfahan Social Security Organization, Isfahan, Iran , Masssah, Laleh Department of Microbiology - Clinical Laboratory of Dr. Gharazi Hospital - Isfahan Social Security Organization, Isfahan, Iran , Norouzi, Zohreh Department of Microbiology - Clinical Laboratory of Dr. Gharazi Hospital - Isfahan Social Security Organization, Isfahan, Iran , Bakhtiyaritabar, Mehrnoush Department of Microbiology - Clinical Laboratory of Dr. Gharazi Hospital - Isfahan Social Security Organization, Isfahan, Iran , Moayednia, Saeed Department of Microbiology - Clinical Laboratory of Alzahra Medical Center, Isfahan, Iran , Shokri, Dariush Nosocomial Infection Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Mikhak, Mahin Department of Microbiology - Clinical Laboratory of Dr. Shariati Hospital - Isfahan Social Security Organization, Isfahan, Iran , Rahmani, Majid Department of Microbiology - Clinical Laboratory of Dr. Gharazi Hospital - Isfahan Social Security Organization, Isfahan, Iran , Hashemi, Mohammad Cardiovascular Department - Interventional Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Etminani, Reza Department of Hospitals Supervision and Accreditation - Vice-Chancellery for Clinical Affairs - Isfahan University of Medical Sciences, Isfahan, Iran , Ahmadi, Nasrin Vice-Chancellery for Clinical Affairs - Isfahan Social Security Organization, Isfahan, Iran , Akhlaghi, Mahboubeh Student Research Committee - Isfahan University of Medical Sciences, Isfahan, Iran , Kelishadi, Roya Child Growth and Development Research Center - Research Institute for Primordial Prevention of Non-Communicable Disease - Isfahan University of Medical Sciences - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
Background: Isfahan Antibiotic Resistance Surveillance System‑1 has been instituted in Isfahan, Iran
to construct a project for surveillance of clinically significant bacteria, and to help raise a logic regional
stewardship program for prevention and control of disseminating‑resistant organisms. Methods: During
March 2016 to March 2018, an antibiotic resistance surveillance system was designed and implemented
by Isfahan Infectious Diseases and Tropical Medicine Research Center. The surveillance program was
implemented in three general hospitals in Isfahan. In addition to the routine microbiology data, clinical
data (differentiation between true infections and contamination, healthcare‑associated infections (HCAI)
and community‑acquired infections (CAI), as well as determination of the infection site) were obtained
and analyzed by WHONET software. Results: During a 2‑year period, from 7056 samples that revealed
growth of bacteria, 3632 (51.5%) isolates were detected as contamination and 3424 (48.5%) true
bacterial isolates were identified. Of these, about 32% of isolates were recognized as HCAI. Totally, the
most recognized infections were urinary tract infection, bloodstream infection and skin and soft tissue
infections. In patients with HCAIs, 70% of isolates were gram negative and in patients with CAIs 73%
isolates were gram negative bacteria. Conclusions: The strength of the project is gathering enough
clinical information in addition to microbiologic data, which would increase application of the results
for empiric treatment and prevention of the infectious diseases in clinical settings.
