Title of article :
Effect of Admission Time on the Outcomes of Liver Cirrhosis with Acute Upper Gastrointestinal Bleeding: Regular Hours versus Off-Hours Admission
Author/Authors :
Li, Yingying Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Han, Bing Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Li, Hongyu Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Song, Tingxue Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Bao, Wenchun Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Wang, Ran Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Bai, Zhaohui Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Zheng, Kexin Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Li, Qianqian Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Guo, Xiaozhong Department of Gastroenterology - General Hospital of Shenyang Military Area, China , Qi, Xingshun Department of Gastroenterology - General Hospital of Shenyang Military Area, China
Pages :
14
From page :
1
To page :
14
Abstract :
Background and Aims Acute upper gastrointestinal bleeding (AUGIB) is a lethal complication of liver cirrhosis. We aimed to compare the outcomes of patients with liver cirrhosis and AUGIB who were admitted to hospital on regular hours and off-hours. Methods This retrospective study screened all cirrhotic patients with AUGIB who were admitted to our hospital from January 2010 to June 2014 for the test cohort and from December 2014 to March 2018 for the validation cohort. A 1:1 propensity score matching analysis was performed to adjust the Child-Pugh and MELD scores. In-hospital mortality, 5-day rebleeding rate, length of stay, and total payment were primary outcomes. Results Overall, 826 and 173 patients with liver cirrhosis and AUGIB were included in the test and validation cohorts, respectively. After propensity score matching, 226 and 40 patients were included in the test and validation cohorts, respectively. The overall analysis of the test cohort found significantly higher Child-Pugh score (P=0.006), 5-day rebleeding rate (18.69% versus 10.72%, P=0.001), and total payment (¥25,906.83 versus ¥22,017.42, P<0.001) in patients admitted on off-hours. By contrast, the overall analysis of the validation cohort did not find any difference in Child-Pugh score, 5-day rebleeding, in-hospital mortality, length of stay, or hospital payment between patients admitted on regular hours and off-hours. Similarly, the propensity score matching analyses of both test and validation cohorts found no difference in these primary outcomes between the two groups. Conclusions Off-hours admission might not be negatively associated with the outcomes of patients with liver cirrhosis and AUGIB.
Keywords :
Effect of Admission Time , Liver Cirrhosis , Acute Upper Gastrointestinal Bleeding , Regular Hours versus
Journal title :
Canadian Journal of Gastroenterology and Hepatology
Serial Year :
2018
Full Text URL :
Record number :
2610949
Link To Document :
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