Title of article :
Cutaneous Basal Cell Carcinoma with Lymph Node andPulmonary Metastases
Author/Authors :
R ̈ubben, Albert Department of Dermatology - Euregional Skin Cancer Center - University Hospital of the RWTH-Aachen - Aachen, Germany , Wahl, Renate U. Department of Dermatology - Euregional Skin Cancer Center - University Hospital of the RWTH-Aachen - Aachen, Germany , Cacchi, Claudio Department of Pathology - University Hospital of the RWTH-Aachen - Aachen, Germany
Abstract :
Basal cell carcinoma (BCC) is the most common skin cancer. Metastatic BCC is an extraordinary rare finding observed in only0.5% of all cases. Until the introduction of the small molecule hedgehog inhibitor vismodegib, patients with metastatic BCC weretreated with chemotherapy, most frequently platinum-based with mixed responses to therapy. We present the case of a 55-year-oldCaucasianmanwhosufferedfromBCConhisleftarmwithlymphnodeandpulmonarymetastases.Sonichedgehogblockadewith vismodegib only induced a short remission, and the patient succumbed to the cancer
Keywords :
Cutaneous Basal Cell Carcinoma , Lymph Node , Pulmonary Metastases , Basal cell carcinoma (BCC)
Journal title :
Case Reports in Oncological Medicine
