Title of article :
Elective Splenectomy Combined with Modified Hassab's or Sugiura Procedure for Portal Hypertension in Decompensated Cirrhosis
Author/Authors :
Zhang, Ya-wu Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China , Wei, Feng-xian Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China , Wei, Zhen-gang Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China , Wang, Gen-nian Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China , Wang, Man-cai Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China , Zhang, You-cheng Department of General Surgery - Lanzhou University Second Hospital, Lanzhou, China
Pages :
7
From page :
1
To page :
7
Abstract :
Objective Portal hypertension is a major complication of decompensated cirrhosis. In China, modified Hassab's and Sugiura procedure are the two major methods of nonshunting surgery. This study aims to compare the efficacy and safety of the two procedures for portal hypertension. Method Between January 1994 and December 2009, 172 elective patients diagnosed with decompensated cirrhosis with significant hypersplenism adopted elective splenectomy for hypersplenism, and also modified Hassab's (n = 91) or Sugiura (n = 81) procedure was additionally performed to reduce the risk of variceal bleeding. Postoperative mortality and morbidity data were collected, and a retrospectively comparative analysis was conducted. Results All of the patients were treated successfully without death during operation, and no variceal bleeding occurred during hospitalization. There were 4 (4.4%) deaths in Hassab's group and 3 (3.7%) deaths in Sugiura group postoperatively (P > 0.05). During follow-up, the survival rate was 90.2%, 82.42%, and 71.43% in Hassab's group and 96.29%, 81.48%, and 75.31% in Sugiura group in 1, 3, and 5 years (P > 0.05). There were 22/71 and 12/63 patients in each groups who suffered no deadly variceal bleeding (P = 0.11). Bleeding related death and no bleeding related death occurred in 7/23 and 3/13 patients in each group (P = 0.26 and 0.14, respectively). Conclusion Elective splenectomy combined with modified Sugiura procedure seemed to be associated with a reduced trend of no deadly variceal bleeding compared with Hassab's procedure. As statistical significance was not found, further large scale and prospective study was warranted.
Keywords :
Elective Splenectomy Combined , Modified Hassab's , Sugiura Procedure , Portal Hypertension , Decompensated Cirrhosis
Journal title :
Canadian Journal of Gastroenterology and Hepatology
Serial Year :
2019
Full Text URL :
Record number :
2611290
Link To Document :
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