Solitary Skull Metastasis as the First Presentation ofa Metachronous Primary Lung Cancer in a Survivor fromPancreatic Cancer

Skull metastasis from lung cancer is relatively common, yet the first presentation for this malignant disease is a rare occurrence.We herein report a case of a 54-year-old female, who had a good outcome following Whipple procedure for periampullaryadenocarcinoma five years before her current presentation. During a routine follow-up, she was found to have a slowly progressivepainless right parietal swelling. The systemic screening workup revealed no abdominal disease, but a solitary pulmonary nodule wasidentified. The presence of these two lesions raised the diagnosis of metastases from a previously treated pancreatic adenocarcinoma.The patient underwent complete excision of the skull lesion and subsequent lung biopsy, both of which proved on histopathologicalexamination to be consistent with a primary lung cancer. This case emphasizes the importance of imaging and histopathologicalcorrelation in the diagnosis of solitary skull metastases and their effect on the subsequent management