Author/Authors :
Mitropoulou, Georgia Pathology Department - “Agia Sofia” Children’s Hospital - Athens, Greece , Zizi-Sermpetzoglou, Adamantia Pathology Department - “Tzaneion” General Hospital - Piraeus, Greece , Kountourogiannis, Athanasios Pathology Department - “Tzaneion” General Hospital - Piraeus, Greece , Myoteri, Despoina Pathology Department - “Tzaneion” General Hospital - Piraeus, Greece , Moschouris, Hippokrates Radiology Department - “Tzaneion” General Hospital - Piraeus, Greece , Dellaportas, Dionysios Department of Surgery - University Hospital “Aretaieion”- Athens, Greece
Abstract :
lasmacytoma is an uncommon plasma cell neoplasm and its localized form is solitary plasmacytoma of the boneand solitary extramedullary plasmacytoma. Solitary plasmacytoma of the mesentery is extremely rare, reported only in a handfulof cases.Case Presentation. A 47-year-old man with nonspecific abdominal complains was found to have an ill-defined masson his mesenteric root. Laparoscopic biopsy and stepwise histopathological examination revealed a mesenteric plasmacytoma,and extensive imaging and laboratory investigations led to the diagnosis of the solitary mesenteric plasmacytoma. The patientunderwent definitive radiotherapy and remains under remission one year later.Discussion. Plasma cell dyscrasias include a variantof proliferative disease, characterized by clonal expansion of bone marrow plasma cells, producing a massive quantity of monoclonalimmunoglobulin called paraprotein or M-protein. Solitary extramedullary plasmacytoma accounts for only 3–5% of all plasma cellneoplasms. Meticulous adherence to the established diagnostic criteria helps the clinician to set the correct, yet very unusual andunexpected diagnosis.