Rare Presentation of Primary ExtramedullaryPlasmacytoma as Lip Lesion

Malignant plasma cell proliferation can be presented as part of disseminated disease of multiple myeloma, as solitary plasmacytomaof bone, or in soft tissue as extramedullary plasmacytoma. Extramedullary plasmacytomas represented approximately 3% of allplasma cell proliferation. Approximately 80% of extramedullary plasmacytomas occur in the head and neck region while the other4% occur in the skin and to a lesser extent in the lip. In this paper, we report a rare case of primary cutaneous plasmacytomainvolving the lip in a 65-year-old male. The patient presented with a nonhealing lower lip sore for the past 3 years. Upon furtherworkup, there was no evidence of multiple myeloma or light chain disease. The patient was treated with radiation therapy and hislast follow-up revealed no evidence of multiple myeloma or light chain disease.