Title of article :
Computational Fluid Dynamics Characterization of Two Patient-Specific Systemic-to-Pulmonary Shunts before and after Operation
Author/Authors :
Zhang, Neichuan School of Mechanical and Automotive Engineering - South China University of Technology - Guangzhou - Guangdong, China , Yuan, Haiyun Department of Cardiac Surgery - Guangdong Cardiovascular Institute - Guangdong Provincial Key Laboratory of South China Structural Heart Disease - Guangdong Provincial People’s Hospital - Guangdong Academy of Medical Sciences - Guangzhou, China , Chen, Xiangyu School of Mechanical and Automotive Engineering - South China University of Technology - Guangzhou - Guangdong, China , Liu, Jiawei School of Mechanical and Automotive Engineering - South China University of Technology - Guangzhou - Guangdong, China , Jian, Qifei School of Mechanical and Automotive Engineering - South China University of Technology - Guangzhou - Guangdong, China , Huang, Meiping Department of Catheterization Lab - Guangdong Cardiovascular Institute - Guangdong Provincial Key Laboratory of South China Structural Heart Disease - Guangdong Provincial People’s Hospital - Guangdong Academy of Medical Sciences - Guangzhou, China , Zhang, Kai School of Medicine - South China University of Technology - Guangzhou, China
Abstract :
Studying the haemodynamics of the central shunt (CS) and modified Blalock–Taussig shunt (MBTS) benefits the improvement of
postoperative recovery for patients with an aorta-pulmonary shunt. Shunt configurations, including CS and MBTS, are virtually
reconstructed for infants A and B based on preoperative CTdata, and three-dimensional models of A, 11 months after CS, and B, 8
months after MBTS, are reconstructed based on postoperative CT data. A series of parameters including energy loss, wall shear
stress, and shunt ratio are computed from simulation to analyse the haemodynamics of CS and MBTS. Our results showed that the
shunt ratio of the CS is approximately 30% higher than the MBTS and velocity distribution in the left pulmonary artery (LPA) and
right pulmonary artery (RPA) was closer to a natural development in the CS than the MBTS. However, energy loss of the MBTS is
lower, and the MBTS can provide more symmetric pulmonary artery (PA) flow than the CS. With the growth of infants A and B,
the shunt ratio of infants was decreased, but maximum wall shear stress and the distribution region of high wall shear stress (WSS)
were increased, which raises the probability of thrombosis. For infant A, the preoperative abnormal PA structure directly resulted
in asymmetric growth of PA after operation, and the LPA/RPA ratio decreased from 0.49 to 0.25. Insufficient reserved length of
the MBTS led to traction phenomena with the growth of infant B; on the one hand, it increased the eddy current, and on the other
hand, it increased the flow resistance of anastomosis, promoting asymmetric PA flow.
Keywords :
Dynamics , Patient-Specific , Systemic-to-Pulmonary , CT
Journal title :
Computational and Mathematical Methods in Medicine
