Title of article :
Concomitant Transverse Myelitis and Acute AxonalSensory-Motor Neuropathy in an Elderly Patient
Author/Authors :
Nitrini, R Department of Neurology - University of Sao Paulo - Sao Paulo - SP, Brazil , Oliveira, L. M. Department of Neurology - University of Sao Paulo - Sao Paulo - SP, Brazil , Cury, R. G. Department of Neurology - University of Sao Paulo - Sao Paulo - SP, Brazil , Castro, L. H. Department of Neurology - University of Sao Paulo - Sao Paulo - SP, Brazil
Abstract :
Diagnosing concomitant transverse myelitis (TM) and Guillain-Barr ́e syndrome (GBS) can be challenging. We report a case ofan elderly patient presenting with acute sensory and motor disturbances in the four limbs, associated with urinary retention,ophthalmoparesis, facial weakness, and dysarthria. Electrodiagnostic studies were consistent with acute motor sensory axonalneuropathy (AMSAN), and imaging showed a longitudinally extensive tumefactive contrast-enhancing hyperintense spinal cordlesion extending from T6 to the cone. Concomitant AMSAN and TM have not been previously reported in the elderly. ComorbidTM and other GBS variants have been previously reported. Intravenous methylprednisolone, plasma exchange, cyclophosphamide,or combination therapies are usually used, although there are no randomized controlled studies regarding treatment choices.
Keywords :
Concomitant Transverse Myelitis , Acute Axona lSensory-Motor Neuropathy , Elderly Patient , GBS , Diagnosing concomitant transverse myelitis (TM)
Journal title :
Case Reports in Immunology