Antihypertensive Medications in Hypertension Control in Male Industrial Employees: a Retrospective Cohort Study

Aims Hypertension control is one of the most important healthcare issues in all societies. One way to control high blood pressure is to use antihypertensive medications. Therefore, this research was to study the effect of antihypertensive drugs on changing blood pressure, Body Mass Index, and Framingham Risk Score. Instrument Methods This retrospective cohort study (from January 2014 to January 2018) was done on male workers who work in Mobarakeh steel company using the census method by referring to the workers’ medical records. The case group (n=642) was hypertensive people who took medications for controlling hypertension, and the control group (n=1555) was healthy people without using any hypertension drug. The FRS is a gender-specific algorithm used to estimate the 10-year risk of cardiovascular in individuals. The blood pressure of both arms was measured by three general practitioners using a calibrated portable or wall mounted Baumometer sphygmomanometer Kompak Model-260mmHg. Data were analyzed by independent t-test and multilevel modeling using R 3.2.1 software. Findings 2197 male workers participate. This study showed that changes in SBP, DBP, and FR’s variables during 2014 to 2019 in the case group compared to the control group had a significant decrease (p 0.001). Nevertheless, this decrease was not significant for the BMI (p=0.588). Conclusion The use of antihypertensive drugs is a very effective method in controlling hypertension patients. Therefore, the priority of pharmacological method in the treatment of this patient is much more effective than other methods.