Title of article :
Synthesis and antibacterial activities of novel 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9H-carbazol-1-yl) ethanone and 1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone
Author/Authors :
Sathiya ، Murugesan PG Research Department of Chemistry - Muthurangam Government Arts College (Autonomous) , Guhanathan ، Selvam PG Research Department of Chemistry - Muthurangam Government Arts College (Autonomous)
Abstract :
Nitrogen containing hetero cyclic compounds constitute the interior structure of a number of biologically attracted compounds against bacteria and fungi. The synthesis of carbazole derivatives have been desire due to their importance in medicinal field. Enhanced approach of Fischer’s synthesis followed by bromoacetylation have been used to synthesis four different carbazole derivatives, namely 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9H-carbazol-1-yl) ethanone,1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone. The synthesized compounds were identified and confirmed using spectral techniques Viz, FTIR, 1H NMR, 13C NMR, MASS Spectroscopy. Antibacterial evaluation of synthesized compounds found to have pronozed antibacterial activity.
Keywords :
Acetic acid , Bromoacetyl bromide , Ciprofloxacin , 1 , bromo , 2 , (6 , bromo , 1 , 2 , 3 , 4 , tetrahydro , 9H , carbazol , 1 , yl) ethanone
Journal title :
International Journal of New Chemistry
Journal title :
International Journal of New Chemistry