Title of article
Synthesis and antibacterial activities of novel 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9H-carbazol-1-yl) ethanone and 1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone
Author/Authors
Sathiya ، Murugesan PG Research Department of Chemistry - Muthurangam Government Arts College (Autonomous) , Guhanathan ، Selvam PG Research Department of Chemistry - Muthurangam Government Arts College (Autonomous)
From page
142
To page
148
Abstract
Nitrogen containing hetero cyclic compounds constitute the interior structure of a number of biologically attracted compounds against bacteria and fungi. The synthesis of carbazole derivatives have been desire due to their importance in medicinal field. Enhanced approach of Fischer’s synthesis followed by bromoacetylation have been used to synthesis four different carbazole derivatives, namely 1-bromo-2-(6-bromo-1,2,3,4-tetrahydro-9H-carbazol-1-yl) ethanone,1-bromo-2-(5-bromo-1,2,3-trihydrocyclopenta[b]indole-1-yl) ethanone. The synthesized compounds were identified and confirmed using spectral techniques Viz, FTIR, 1H NMR, 13C NMR, MASS Spectroscopy. Antibacterial evaluation of synthesized compounds found to have pronozed antibacterial activity.
Keywords
Acetic acid , Bromoacetyl bromide , Ciprofloxacin , 1 , bromo , 2 , (6 , bromo , 1 , 2 , 3 , 4 , tetrahydro , 9H , carbazol , 1 , yl) ethanone
Journal title
International Journal of New Chemistry
Journal title
International Journal of New Chemistry
Record number
2614058
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