Effect of Fluoride Varnish Containing CPP-ACP onPreventing Enamel Erosion

This study aimed to investigate the effect of a fluoride varnish with added casein phosphopeptide-amorphous calcium phosphatetreatment on the prevention of enamel erosion, and it compared the results with those of other fluoride varnishes. Fifty enamelspecimens obtained from bovine incisors were randomly divided into five groups (𝑛=10) based on the type of surface pretreatmentused: intact enamel (Group 1); intact enamel+erosive cycles (Group 2); intact enamel+MI varnish+erosive cycles (Group 3); intactenamel+Clinpro White varnish+erosive cycles (Group 4); and intact enamel+Duraphat varnish+erosive cycles (Group 5). Thespecimens were subjected to erosive cycles for five days. The surface roughness was evaluated using atomic force microscopy. Theresults were statistically analyzed using one-way ANOVA and Tukey’s tests. Group 1 had the smoothest surfaces. After the erosivecycles, the greatest surface roughness values were observed in Group 2, followed by Groups 5, 4, and 3, respectively. Statisticallysignificant differences were observed among all groups (𝑝<0.05). The application of fluoride varnishes had some positive effects onpreventing enamel erosion; however, the most effective agent was fluoride varnish with added casein phosphopeptide-amorphouscalcium phosphate.