Author/Authors :
Mendonça , Vanessa A. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Lage , Vanessa K. S. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Lacerda , Ana Cristina R. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Neves, Camila D. C. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Chaves, Maria Gabriela A. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Soares, Aline A. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Lima, Liliana P. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Martins, Jeanne B. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Matos, Mariana A. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Leite, Hércules R. Universidade Federal dos Vales do Jequitinhonha e Mucuri - Diamantina - MG, Brazil , Vieira , Érica L. M. Minas Gerais, Brazil , Teixeira ,Antônio L. Minas Gerais, Brazil , Oliveira, Vinicius Cunha Diamantina - Minas Gerais, Brazil
Abstract :
Whole-body vibration (WBV) has gained prominence in the rehabilitation of individuals with chronic obstructive pulmonary
disease (COPD) because it is a safe and low intensity exercise that promises beneficial effects on physical performance and quality
of life. However, its effects on plasma cytokine levels in COPD are still unclear. The aim of the current study was to investigate the
acute effects of WBV on inflammatory biomarkers in people with COPD. Twenty-six participants, COPD people (n=13) and healthy
controls (n=13), were included. Both groups performed WBV at amplitude of 2 mm and frequency of vibration of 35 Hz, during six
series of 30 seconds. They were assessed for lung function, body composition, 6-minute walking test (6MWT), handgrip strength
test, plasma concentrations of interleukin (IL), IL-6, IL-8, and IL-10, and soluble tumor necrosis factor alpha (TNF-𝛼) receptors
(sTNFR-1 and sTNFR-2). People with COPD had moderate disease [forced expiratory volume in the first second (FEV1) = 58.1%],
as well as a worse performance in the 6MWT. The plasma cytokine profile at rest showed that participants with COPD had higher
levels of IL-8 and lower levels of IL-10. After one session of WBV, we found an increased plasma IL-10 level in the COPD group,
with similar levels for healthy controls. One session of WBV modified the plasma IL-10 level. No effects were found on the other
investigated cytokines
Keywords :
Acute Effects , Whole-Body Vibration , Inflammatory Markers , People , Chronic Obstructive Pulmonary Disease , A Pilot Study
