Author/Authors :
Pellico, Juan Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and Centro de Investigacion Biomedicaen Red de Enfermedades Respiratorias (CIBERES) - Madrid, Spain , Llop, Jordi Radiochemistry and Nuclear Imaging Group - CIC biomaGUNE - Paseo Miramon - Donostia, Spain , Fernández-Barahona, Irene Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and Centro de Investigacion Biomedicaen Red de Enfermedades Respiratorias (CIBERES) - Madrid, Spain , Bhavesh, Riju Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and Centro de Investigacion Biomedicaen Red de Enfermedades Respiratorias (CIBERES) - Madrid, Spain , Ruiz-Cabello, Jesús Departamento Quımica Fısica - Facultad de Farmacia - Universidad Complutense de Madrid - Madrid, Spain , Herranz, Fernando Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and Centro de Investigacion Biomedicaen Red de Enfermedades Respiratorias (CIBERES) - Madrid, Spain
Abstract :
The combination of the size-dependent properties of nanomaterials with radioisotopes is emerging as a novel tool for molecular
imaging. There are numerous examples already showing how the controlled synthesis of nanoparticles and the incorporation of
a radioisotope in the nanostructure offer new features beyond the simple addition of different components. Among the different
nanomaterials, iron oxide-based nanoparticles are the most used in imaging because of their versatility. In this review, we will study
the different radioisotopes for biomedical imaging, how to incorporate them within the nanoparticles, and what applications they
can be used for. Our focus is directed towards what is new in this field, what the nanoparticles can offer to the field of nuclear
imaging, and the radioisotopes hybridized with nanomaterials for use in molecular imaging.
Keywords :
Oxide , Enhanced , Molecular , NM , MI