Title of article :
Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
Author/Authors :
Purwanto, Diana Shintawati Department of Clinical Pathology - Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Loho, Tonny Department of Clinical Pathology - Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Tafroji, Wisnu Molecular Bacteriology Unit - Eijkman Institute for Molecular Biology, Jakarta, Indonesia , Mangunatmadja, Irawan Department of Child Health - Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Immanuel, Suzanna Department of Clinical Pathology - Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Timan, Ina Susianti Department of Clinical Pathology - Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Yusra, Yusra Department of Clinical Pathology - Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia , Safari, Dodi Molecular Bacteriology Unit - Eijkman Institute for Molecular Biology, Jakarta, Indonesia
Pages :
6
From page :
1
To page :
6
Abstract :
CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia.
Keywords :
Streptococcus pneumoniae , meningitis , CSF infection , serotype 6B , antibiotic susceptibility
Journal title :
Access Microbiology
Serial Year :
2020
Full Text URL :
Record number :
2616795
Link To Document :
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