Author/Authors :
Capasso, Letizia Department of Translational Medical Science - University Federico II, Naples, Italy , Cerullo, Julia Department of Translational Medical Science - University Federico II, Naples, Italy , Lo Vecchio, Andrea Department of Translational Medical Science - University Federico II, Naples, Italy , Coppola, Clara Department of Translational Medical Science - University Federico II, Naples, Italy , Lepore, Lorenza Department of Translational Medical Science - University Federico II, Naples, Italy , Marra, Valentina Department of Translational Medical Science - University Federico II, Naples, Italy , Antonaki, Eleni Department of Molecular Medicine and Medical Biotechnology - Division of Bacteriology and Mycology - University of Naples Federico II, Naples, Italy , Raimondi, Francesco Department of Translational Medical Science - University Federico II, Naples, Italy
Abstract :
We report an unusual and rare case of infection from methicillin resistant Staphylococcus au-reus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pour clinical condition. This very aggressive presentation of infection from MRSA push us to test Panton- Valentine leukocidin resulted positive and to test contacts to discover the bearer of the germ. MRSA producing Panton-Valentine leukocidin is an unusual case of infection in preterm neonate that has not been reported elsewhere. A very aggressive sepsis in neonates from Staphilococcus aureus should evoke the need to test Panton-Valentine leukocidin to rapidly establish an appropriate treatment. We underline also the impor-tance to test contacts to establish promptly a decontaminant therapy. (www.actabiomedica.it)
Keywords :
methicillin resistant Staphylococcus aureus , Panton-Valentine leukocidin , neonate , late onset sepsis , case report