Molecular Imaging: In Vivo Agents for the Diagnosis and Treatment of Cancer

Molecular imaging continues to advance the goal of improving diagnosis and treatment in cancer. is special issue examines a cross section of the current basic and clinical research across imaging modalities, probes, and molecular targets. e issue articles permit comparison of the advantages and limitations of varied modalities, including PET, SPECT, CT, MRI, ultrasound imaging, and fluorescence imaging. e corresponding agents in development are able to interact with many targets of relevance to cancer. Highly sensitive and specific in vivo agents permit visualization of receptor systems, enzymes, and proteins involved in cancer initiation, maintenance, and spread. As another dimension of cancer targeting, molecular probes for the tumor microenvironment, including stromal, endothelial, and immune cells, are increasingly recognized as key factors in attacking cancer.