Title of article
Use of fibrinogen and thrombin sponge in pediatric split liver transplantation
Author/Authors
Vicentine, Fernando Pompeu Piza Universidade Federal de São Paulo (UNIFESP), Brazil , Gonzalez, Adriano Miziara Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Beninni, Barbara Burza Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Azevedo, Ramiro Anthero de Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Linhares, Marcelo Moura Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Goldenberg, Alberto Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Lopes, Gaspar de Jesus Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Martins, Jose Luiz Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Salzedas, Alcides Augusto Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil
Pages
7
From page
673
To page
679
Abstract
Purpose:
To analyze the use of this sponge in pediatric patients undergoing split-liver transplantation.
Methods:
Retrospective study, including 35 pediatric patients undergoing split-liver transplantation, divided into two groups according to the use of the sponge: 18 patients in Group A (no sponge) and 17 in Group B (with sponge).
Results:
The characteristics of recipients and donors were similar. We observed greater number of reoperation due to bleeding in the wound area in Group A (10 patients - 55.5%) than in Group B (3 patients - 17.6%); p = 0.035. The median volume of red blood cells transfused in Group A was significantly higher (73.4 ± 102.38 mL/kg) than that in Group B (35.1 ± 41.67 mL/kg); p = 0.048. Regarding bile leak there was no statistical difference.
Conclusion:
The use of the human fibrinogen and thrombin sponge, required lower volume of red blood cell transfusion and presented lower reoperation rates due to bleeding in the wound area.
Keywords
Liver Transplantation , Homeostasis , Fibrinogen , Thrombin
Journal title
Acta Cirurgica Brasileira
Serial Year
2017
Record number
2617785
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