• Title of article

    Crystal structure of (1S,3R,8R,10S)-2,2-di­chloro-10-hy­dr­oxy-3,7,7,10-tetra­methyl­tri­cyclo­[6.4.0.01,3]dodecan-9-one

  • Author/Authors

    Benzalim,Ahmed Laboratoire de Physico-Chimie Moléculaire et Synthèse Organique - Département de Chimie - Faculté des Sciences, Morocco , Auhmani, Aziz Laboratoire de Physico-Chimie Moléculaire et Synthèse Organique - Département de Chimie - Faculté des Sciences, Morocco , Daran, Jean-Claude Laboratoire de Chimie de Coordination,, France , Ait Itto, My Youssef Laboratoire de Physico-Chimie Moléculaire et Synthèse Organique - Département de Chimie - Faculté des Sciences, Morocco , Abdelwaheda, Auhmani Laboratoire de Physico-Chimie Moléculaire et Synthèse Organique - Département de Chimie - Faculté des Sciences, Morocco

  • Pages
    12
  • From page
    1
  • To page
    12
  • Abstract
    The asymmetric unit of the title compound, C16H24Cl2O2, contains two independent mol­ecules (A and B) which are built from three fused rings, viz. a seven-membered heptane ring, a six-membered cyclo­hexyl ring bearing a ketone and an alcohol group, and a cyclo­propane ring bearing two Cl atoms. In the crystal, the two mol­ecules are linked via two O—H⋯O hydrogen bonds, forming an A–B dimer with an R22(10) ring motif. The A mol­ecules of these dimers are linked via a C—H⋯O hydrogen bond, forming chains propagating along the a-axis direction. Both mol­ecules have the same absolute configuration, i.e. 1S,3R,8R,10S, which is based on the synthetic pathway and further confirmed by resonant scattering [Flack parameter = 0.03 (5)].
  • Keywords
    crystal structure , hydrogen bonding , absolute configuration , natural products , asymmetric synthesis
  • Journal title
    Acta Crystallographica Section E: Crystallographic Communications
  • Serial Year
    2016
  • Record number

    2617914