Title of article
Effect of ovariectomy in bone structure of mandibular condyle
Author/Authors
Constâncio, Cristina Universidade do Sagrado Coração (USC), Bauru-SP, Brazil , Pagani, Bruna Trazzi USC, Bauru-SP, Brazil , Azevedo, Regina Magrini Guedes de USC, BaurSP, Brazil , Grion, Dalva Pazzini Department of Biological and Health Sciences - Centro Universitário de Adamantina (UNIFAI), Adamantina-SP, Brazil , Marques, Leonardo Universidade de Marília (UNIMAR), Brazil , Kinoshita, Angela USC, Bauru-SP, Brazil
Pages
10
From page
843
To page
852
Abstract
Purpose:
To evaluate the bone structure of the mandibular condyle through an animal model, after ovariectomy.
Methods:
Thirty-six female Wistar rats were divided into 2 groups. The OVX group was submitted to bilateral ovariectomy, the SHAM group underwent the same surgical treatment, but without removal of the ovaries. After 90, 105 and 135 days after surgery, six animals from each group were submitted to euthanasia and the part containing the condyle was removed.
Results:
The microscopic analysis shows an increase in marrow spaces over time in the OVX group. The morphometric study shows reduction in the amount of bone tissue in the OVX group 135 days period in comparison with for the initial period (90 days) (p <0.05, ANOVA, Tukey).
Conclusion:
The estrogen deficiency also affects the bone structure of the condyle.
Keywords
Mandibular Condyle , Osteoporosis , Ovariectomy , Rats
Journal title
Acta Cirurgica Brasileira
Serial Year
2017
Record number
2617977
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