Title of article :
Crystal structure of (1RS,21SR,22RS,24SR)-28-oxo-24-propyl-8,11,14-trioxa-24,27-diazapentacyclo[19.5.1.122,26.02,7.015,20]octacosa-2,4,6,15(20),16,18-hexaene acetic acid monosolvate
Author/Authors :
Hieu, Truong Hong Institute of Chemistry - Vietnam Academy of Science and Technology, Vietnam , Anh, Le Tuan Department of Chemistry - Vietnam National University, Vietnam , Soldatenkov, Anatoly T. Organic Chemistry Department - Peoples' Friendship University of Russia, Russian Federation , Tuyen, Nguyen Van Institute of Chemistry - Vietnam Academy of Science and Technology, Vietnam , Khrustalevd, Victor N. norganic Chemistry Department - Peoples' Friendship University of Russia, Russian Federation
Abstract :
The title compound, C26H32N2O4(M)·C2H4O2, (I), is the product of the Petrenko–Kritchenko condensation of N-propylpiperidinone with 1,5-bis(2-formylphenoxy)-3-oxapentane and ammonium acetate. In M, the aza-14-crown-3-ether ring adopts a bowl conformation, with the configuration of the C—O—C—C —O—C—C—O—C polyether chain being t–g(−)–t–t–g(+)–t (t = trans, 180°; g = gauche, ±60°). The dihedral angle between the planes of the benzene rings fused to the aza-14-crown-4-ether moiety is 62.75 (5)°. The central piperidinone ring has a boat conformation, whereas the terminal piperidinone ring adopts a chair conformation. The boat conformation of the central piperidinone ring is supported by the bifurcated intramolecular N—H⋯O hydrogen bond. In the crystal, each solvent molecule is linked to molecule M via strong O—H⋯N hydrogen bonding, forming hydrogen-bonded pairs of molecules, which further interact through weak C—H⋯O hydrogen bonds, forming layers parallel to the ac plane.
Keywords :
aza-14-crown-3-ether , crystal structure , Petrenko–Kritchenko condensation
Journal title :
Acta Crystallographica Section E: Crystallographic Communications
