Title of article :
Diagnostic Performance of 18F-FDG PET/CT in Infectious and Inflammatory Diseases according to Published Meta-Analyses
Author/Authors :
Treglia, Giorgio Department of Nuclear Medicine and Molecular Imaging - Lausanne University Hospital - University of Lausanne - Lausanne, Switzerland
Abstract :
To date, several meta-analyses have reported data about the diagnostic performance of 18F-FDG PET/CT in infectious
and inflammatory diseases. This article aims to summarize the published evidence-based data about the diagnostic performance of
18F-FDG PET/CT in this setting. Methods. A comprehensive computer literature search of meta-analyses published in PubMed/
MEDLINE and Cochrane library database from January 2009 through December 2018 and regarding the diagnostic performance
of 18F-FDG PET/CT in infectious and inflammatory diseases was carried out. This combination of key words was used: (i) “PET”
or “positron emission tomography” or “FDG” or “fluorodeoxyglucose” and (ii) meta-analysis. Only records on inflammatory
or infectious diseases were selected. Results. The diagnostic performance of 18F-FDG PET/CT in detecting inflammatory and
infectious diseases has been summarized taking into account 36 meta-analyses published in the literature. Evidence-based data
demonstrated good diagnostic performance of 18F-FDG PET/CT for several inflammatory and infectious diseases, in particular
cardiovascular infectious and inflammatory diseases and some musculoskeletal infections. Conclusions. Evidence-based data
about the diagnostic performance of 18F-FDG PET/CT in infectious and inflammatory diseases are increasing, with good diagnostic performance of this imaging method for some indications. More prospective multicenter studies and cost-effective
analyses are warranted.
Keywords :
18F-FDG , PET/CT , CT
Journal title :
Contrast Media and Molecular Imaging
