Title of article :
Crystal structure of 5-butyl­amino-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde obtained from a microwave-assisted reaction using caesium carbonate as catalyst
Author/Authors :
Macías, Mario A. Department of Chemistry - Universidad de los Andes, Colombia , Orrego-Hernández, Jessica Bioorganic Compounds Research Group - Department of Chemistry - Universidad de los Andes, Colombia , Portilla, Jaime Bioorganic Compounds Research Group - Department of Chemistry - Universidad de los Andes, Colombia
Pages :
8
From page :
1
To page :
8
Abstract :
The title compound, C14H18N4O, synthesized from an unconventional microwave-assisted method using caesium carbonate as catalyst, has an approximately planar conformation with the pyridyl and pyrazole rings inclined by a dihedral angle of 7.94 (3)°, allowing the formation of an intra­molecular N—H⋯N hydrogen bond. The supra­molecular assembly has a three-dimensional arrangement controlled mainly by weak C—H⋯O and C—H⋯π inter­actions.
Keywords :
crystal structure , pharmaceutical compound , hydrogen bonding , nucleophilic substitution , 5-amino­pyrazoles
Journal title :
Acta Crystallographica Section E: Crystallographic Communications
Serial Year :
2016
Full Text URL :
Record number :
2619454
Link To Document :
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