Author/Authors :
Bagley, Sarah M. Department of Medicine - Boston University School of Medicine - Boston Medical Center, Boston, USA , Cabral, Howard School of Public Health - Boston University, Boston, USA , Saia, Kelley Department of Obstetrics and Gynecology - Boston University School of Medicine, Boston Medical Center, Boston, USA , Brown, Alyssa Northeastern University School of Public Health, Boston, USA , Lloyd‑Travaglini, Christine Public , Walley, Alexander Y. Department of Medicine - Boston University School of Medicine - Boston Medical Center, Boston, USA , Rose‑Jacobs, Ruth Department of Pediatrics - Boston University School of Medicine - Boston Medical Center, Boston, USA
Abstract :
Background
Little is known about opioid overdose or naloxone access among pregnant women.
Objectives
The objectives of this study were to determine the prevalence of non-fatal overdose, risk factors for overdose, and naloxone access among third trimester women in treatment for opioid use disorder.
Methods
We collected baseline data from a case management parental-support intervention study. To explore the association of variables with past year overdose, we used Wilcoxon rank-sum test, Chi square or Fisher’s exact tests.
Results
Among 99 participants, 14% (95% CI 7–21%) reported past year overdose and 67% (95% CI 57–76%) had received overdose education and a naloxone kit. Younger age was the only variable associated with past year overdose.
Conclusions
In this sample, past year non-fatal overdose was common, younger age was a risk factor, and most participants had received a naloxone kit. Further work is needed to understand whether younger age is a risk factor in the general population of pregnant women with opioid use disorder and to identify other potential risk factors for overdose in this population
Keywords :
Opioids , Overdose , Pregnancy , Naloxone