Title of article
Crystal structure of 5-benzyl-8-bromo-2-methyl-1,3-oxazolo[4,5-c][1,8]naphthyridin-4(5H)-one
Author/Authors
Vrijdag, Johannes KU Leuven - University of Leuven - Department of Chemistry, Belgium , Bogaert, An Van den KU Leuven - University of Leuven - Department of Chemistry, Belgium , Borggraeve, Wim De KU Leuven - University of Leuven - Department of Chemistry, Belgium , Meervelt, Luc Van KU Leuven - University of Leuven - Department of Chemistry, Belgium
Pages
9
From page
1
To page
9
Abstract
The title compound, C17H12BrN3O2, was unexpectedly isolated during an attempt to synthesize pyridodiazepinediones and identified as an oxazolonaphthyridinone derivative. The almost planar oxazolonaphthyridinone ring (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 61.6 (2)° with the phenyl ring. In the crystal, columns of molecules stacked along the a axis are formed by π–π interactions between the six-membered rings of the oxazolonaphthyridone moieties [centroid-to-centroid distances = 3.494 (2)–3.906 (3) Å], which further interact through C—H⋯π contacts with the phenyl rings.
Keywords
crystal structure , benzodiazepine drugs , π–π stacking , oxazolonaphthyridone
Journal title
Acta Crystallographica Section E: Crystallographic Communications
Serial Year
2017
Record number
2621742
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