Author/Authors :
Marek-Józefowicz, Luiza Chair of Dermatology - Sexually Transmitted Diseases and Immunodermatology - Faculty of Medicine in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Jaracz, Marcin Chair and Department of Clinical Neuropsychology - Faculty of Health Science in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Placek, Waldemar Department of Dermatology - Sexually Transmitted Diseases and Clinical Immunology - Faculty of Medical Sciences - University of Warmia and Mazury, Olsztyn, Poland , Czajkowski, Rafał Chair of Dermatology - Sexually Transmitted Diseases and Immunodermatology - Faculty of Medicine in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Borkowska, Alina Chair and Department of Clinical Neuropsychology - Faculty of Health Science in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland
Abstract :
Introduction
Psoriasis is a chronic inflammatory skin disease, in which an important role is played by psychological factors.
Aim
To evaluate the frontal cognitive functions in patients with psoriasis.
Material and methods
The study included 188 subjects (97 patients with psoriasis and 91 healthy controls). To assess the dorsolateral prefrontal cortex functions, the Trail Making Test and the Stroop test were applied. Severity of psoriasis was assessed by means of the PASI index.
Results
Compared to healthy subjects, psoriatics scored lower in neuropsychological tests assessing memory and executive functions.
Conclusions
Cognitive dysfunction disclosed by neuropsychological assessment of frontal functions was evident in patients with psoriasis.
Keywords :
psoriasis , cognitive functions , executive functions , depression , prefrontal cortex
