Title of article
Crystal structure and Hirshfeld surface analysis of 1-methyl-4-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazin-1-ium 2,5-dihydroxybenzoate propan-2-ol monosolvate
Author/Authors
Natchimuthu, V. Department of Physics - M.Kumarasamy College of Engineering, India , Sharmila, N. Department of Physics - Shrimati Indira Gandhi College, India , Ravi, S. Postgraduate and Research Department of Physics - National College (Autonomous), India
Pages
12
From page
1
To page
12
Abstract
The asymmetric unit of the title salt, C17H21N4S+·C7H5O4−·C3H7OH, consists of an olanzapinium cation, an independent 2,5-dihydroxybenzoate anion and a solvent isopropyl alcohol molecule. The central seven-membered heterocycle is in a boat conformation, while the piperazine ring displays a distorted chair conformation. The dihedral angle between the benzene and thiene rings flanking the diazepine ring is 52.58 (19)°. In the crystal, the anions and cations are connected by N—H⋯O and O—H⋯O hydrogen bonds, forming a three-dimensional network.
Keywords
crystal structure , olanzapine , salt , hydrogen bond , Hirshfeld surface
Journal title
Acta Crystallographica Section E: Crystallographic Communications
Serial Year
2020
Record number
2623568
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