Title of article :
Wound healing complications in oncological patients: perspectives for cellular therapy
Author/Authors :
Deptuła, Milena Department of Embryology - Medical University of Gdansk, Poland , Zieliński, Jacek Department of Surgical Oncology - Medical University of Gdansk, Poland , Wardowska, Anna Department of Clinical Immunology and Transplantology - Medical University of Gdansk, Poland , Pikuła, Michał Department of Clinical Immunology and Transplantology - Medical University of Gdansk, Poland
Abstract :
Various types of cancer are nowadays a serious medical and social problem and a great challenge for modern medicine. The majority of anticancer therapy is based on traditional chemotherapy and radiotherapy. Both of these highly non-specific types of treatment have a number of serious side effects including wound healing complications. Radiotherapy and chemotherapy mostly affect rapidly dividing skin cells (e.g. keratinocytes), as well as fibroblasts, melanocytes, endothelial and immune cells. Currently, there are many strategies to improve wound healing in oncological patients, including various types of dressings, biomaterials, growth factors, and cell therapies.
Keywords :
wounds , cancers , cell therapy
Journal title :
Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
