Author/Authors :
Daoui, Said Laboratory of Applied Chemistry and Environment (LCAE) - Faculty of Sciences - Mohamed I University, Morocco , Baydere, Cemile Department of Physics - Faculty of Arts and Sciences - Ondokuz Mayıs University, Turkey , Kalai, Fouad El Laboratory of Applied Chemistry and Environment (LCAE) - Faculty of Sciences - Mohamed I University, Morocco , Saddik, Rafik Laboratory for Organic Synthesis - Extraction and Valorization- Faculty of Sciences, Ain Chok - University Hassan II, Morocco , Dege, Necmi Department of Physics - Faculty of Arts and Sciences - Ondokuz Mayıs University, Turkey , Karrouchi, Khalid Laboratory of Plant Chemistry - Organic and Bioorganic Synthesis, URAC23 - Faculty of Science - BP 1014 - GEOPAC Research Center, Morocco , Benchat, Noureddine Laboratory of Applied Chemistry and Environment (LCAE) - Faculty of Sciences - Mohamed I University, Morocco
Abstract :
In the title compound, C13H14N2O3, the dihydropyridazine ring (r.m.s.
deviation = 0.166 A˚ ) has a screw-boat conformation. The dihedral angle
between its mean plane and the benzene ring is 0.77 (12). In the crystal,
intermolecular O—HO hydrogen bonds generate C(5) chains and N—HO
hydrogen bonds produce R2 2 (8) motifs. These types of interactions lead to the
formation of layers parallel to (121). The three-dimensional network is achieved
by C—HO interactions, including R2 4 (8) motifs. Intermolecular interactions
were additionally investigated using Hirshfeld surface analysis and twodimensional fingerprint plots. The most significant contributions to the crystal packing are by HH (43.3%), HC/CH (19.3%), HO/HO (22.6%), CN/NC (3.0%) and HN/NH (5.8%) contacts. C—H interactions
and aromatic – stacking interactions are not observed
Keywords :
pyridazine , crystal structure , hydrogen bonding , Hirshfeld surface analysis
