Title of article :
Crystal structure of (1S,2R)-2-[(3R,4S)-3-methyl-4-phenyl-1,2,3,4-tetra­hydro­isoquinolin-2-yl]-1,2-di­phenyl­ethanol
Author/Authors :
Ali, Karim Ben Laboratoire de Recherche en Energie et Matière pour le Développement des Sciences Nucléaires - Centre National des Sciences et Technologies Nucléaires, Tunisia , Retailleau, Pascal Laboratoire de Recherche en Energie et Matière pour le Développement des Sciences Nucléaires - Centre National des Sciences et Technologies Nucléaires, Tunisia
Pages :
11
From page :
1
To page :
11
Abstract :
The synthesis and crystal structure of the title compound, C30H29NO, are described. This compound is a member of the chiral dihydroisoquinolinederived family, used as building blocks for functional materials and as source of chirality in asymmetric synthesis, and was isolated as one of two diastereomeric -amino alcohols, the title molecule being found to be the (S,R) diastereoisomer. In the crystal, molecules are packed in a herringbone manner parallel to (103) and (103) via weak C—HO and C—H(ring) interactions. Hirshfeld surface analysis showed that the surface contacts are predominantly HH interactions (ca 75%). The crystal studied was refined as a two-component inversion twin.
Keywords :
crystal structure , chiral β-amino alcohol , tetra­hydro­iso­quinoline , hydrogen bond , Hirshfeld surface analysis
Journal title :
Acta Crystallographica Section E: Crystallographic Communications
Serial Year :
2019
Full Text URL :
Record number :
2625247
Link To Document :
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