Title of article
(3,5-Dimethyladamantan-1-yl)ammonium methanesulfonate (memantinium mesylate): synthesis, structure and solid-state properties
Author/Authors
Tuksar, Mihaela PLIVA Croatia Ltd - TAPI Research and Development, Croatia , Rubčić, Mirta Department of Chemistry - Faculty of Science - University of Zagreb, Croatia , Meštrović, Ernest PLIVA Croatia Ltd - TAPI Research and Development, Croatia
Pages
17
From page
1
To page
17
Abstract
The asymmetric unit of the title compound, C12H22N+·CH3O3S−, consists of three (3,5-dimethyladamantan-1-yl)ammonium cations, C12H22N+, and three methanesulfonate anions, CH3O3S−. In the crystal, the cations and anions associate via N—H⋯O hydrogen bonds into layers, parallel to the (001) plane, which include large supramolecular hydrogen-bonded rings.
Keywords
crystal structure , memantine , X-ray diffraction , differential scanning calorimetry (DSC) , thermogravimetric analysis (TGA) , IR spectroscopy
Journal title
Acta Crystallographica Section E: Crystallographic Communications
Serial Year
2019
Record number
2625444
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