Author/Authors :
Modrakowska, Paulina Department of Tissue Engineering - The Ludwik Rydygier Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Balik, Karolina Department of Tissue Engineering - The Ludwik Rydygier Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Maj, Małgorzata Department of Tissue Engineering - The Ludwik Rydygier Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Bajek, Anna Department of Tissue Engineering - The Ludwik Rydygier Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland
Abstract :
Advanced skin carcinomas are a serious therapeutic problem. The statistical analysis shows a continuous increase in the incidence of both melanoma and non-melanoma skin cancers. Traditional therapies are characterized by low effectiveness and patients overall survival is not affected by them. By understanding the molecular pathways that lead to the neoplastic transformation and thanks to the knowledge of the immune system, it is possible to use personalized medicine in novel therapies for advanced skin carcinomas.