Author/Authors :
Hashemipour, Mahin isfahan university of medical sciences - Endocrine Metabolism Research Center, اصفهان, ايران , Moaddab, Mohammad Hassan isfahan university of medical sciences - Isfahan Endocrine and Metabolism Research Center, اصفهان, ايران , Nazem, Masoud isfahan university of medical sciences - School of Medicine, Al-Zahra Hospital - Department of Pediatric Surgery, اصفهان, ايران , Mahzouni, Parvin isfahan university of medical sciences - School of Medicine, Al-Zahra Hospital, - Department of Pathology, اصفهان, ايران , Salek, Mehdi isfahan university of medical sciences - Isfahan Endocrine and Metabolism Research Center, اصفهان, ايران
Abstract :
Ovarian sex cord-stromal tumors, including granulose cell tumors (GCTs), are a group of neoplasms that occur rarely, especially in children. Only 0.1 percent of all ovarian tumors and 4-5 percent of GCTs occur in children. The most common presentation of these tumors in children is precocious puberty. We report a 6 years old girl with isosexual precocity, presented as premature thelarche and vaginal bleeding. Ultrasonography of pelvis showed a hypoechoic solid mass of left ovary. Microscopic features of the resected mass were characteristic of juvenile GCT. Although in most of girls with precocious puberty, the etiology is idiopathic, important causes, such as ovarian tumors must be considered.
