• Title of article

    HUMULENE SESQUITERPENE LACTONES FROM Asteriscus schimperi

  • Author/Authors

    Dawidar, Abdelaziz M. Mansoura University - Faculty of Science - Chemistry Department, Egypt , Ayyad, Seifeddin N. Mansoura University - Faculty of Science - Chemistry Department, Egypt , Abdel-Mogib, Mamdouh Abdel-Mogib Mansoura University - Faculty of Science - Chemistry Department, Egypt , Alarif, Walied M. Mansoura University - Faculty of Science - Chemistry Department, Egypt

  • Pages
    6
  • From page
    137
  • To page
    142
  • Abstract
    Asteriscus schimperi is a rarely distributed species, belongs to the family Composite. This species has not been previously investigated for natural products. In this article we report the isolation and structure elucidation of two bisabolone sesquiterpenes and four humulene sesquiterpene lactones. The bisabolone derivatives are bisabola-2, 10-dien-1-one 1 and 6-hydroxybisabola-2, 10-dien-1-one 2, while the humulene derivatives are 9-oxohumula-4-en-6, 15-olide 3, 9-oxohumula-4, 7 (E)-dien-6,15-olide 4, 9-oxohumula-1 (10) (Z), 4, 7 (E)-trien-6, 15-olide 5, and 9-oxohumula-1 (10) (E), 4, 7 (E)-trien-6, 15-olide 6. The humulene sesquiterpene lactone 4 is a new one since it has not been previously isolated from any natural source. The structure elucidation of the isolated compounds is based on spectral analysis.
  • Arabic abstract
    من الأنواع النادرة و تنتمي إلى العائلة المركبة .Compositae و لم يدرس هذا النوع من قبل لعزل منتجات طبيعية. و في هذا البحث قمنا بفصل و التعرف على لاكتونات أثنين من bisabolone sesquiterpenes و أربعة من .humulene sesquiterpene و مشتقات بيسابولون هي 1 bisabola-2,10-dien-1-one و 6-hydroxybisabola-2,10 ،dien-1-one 2 بينما مشتقات هوميولين هي : 9-oxohumula-4-en-6,15-olide 3, 9-oxohumula-4,7(E)-dien- 6,15-olide 4, oxohumula-1(10)(Z),4,7(E)-trien-6,15-olide 5-9, و 6,15- 9-oxohumula-1(10)(E),4,7(E)-trien- olide 6. و بالنسبة ل 4 humulene sesquiterpene lactone فهو مركب جديد لم يسبق فصله من قبل من أي مصدر طبيعي. و تم التعرف على المركبات التي تم فصلها بالتحاليل الطيفية.
  • Keywords
    Asteriscus schimperi , bisabolone derivatives , HUMULENE SESQUITERPENE LACTONES
  • Journal title
    Journal of Saudi Chemical Society
  • Serial Year
    2005
  • Journal title
    Journal of Saudi Chemical Society
  • Record number

    2626457

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2626457