Title of article :
Endocrine-Disrupting Chemicals Role in Drug Abuser: A Review Study
Author/Authors :
Wiraagni ، Idha Arfianti Department of Pathology, Department of Forensic Medicine and Medicolegal - Faculty of Medicine - University of Malaya , Mohd ، Mustafa Ali Shimadzu‐UM Center for Xenobiotics Studies (SUCXeS), Faculty of Medicine - University of Malaya , Rashid ، Rusdi Abdul Department of Psychological Medicine - Faculty of Medicine - University of Malaya , Mohamad Haron ، Didi Erwandi Bin Shimadzu‐UM Center for Xenobiotics Studies (SUCXeS), Faculty of Medicine - University of Malaya
Abstract :
Endocrine-disrupting Chemicals (EDCs) are exogenous chemicals that influence many aspects of natural hormone actions. Bisphenol is used in the industry, for increasing the thickness and durability of materials in certain plastics and resins. Paraben is used as preservatives in many pharmaceuticals, cosmetics, and some food products. EDCs can increase estrogen levels inside the body, and estrogen itself can increase the monoamine effect (dopamine, serotonin), neuronal excitability, neuropeptide transmitter mechanism, and drug metabolism. In drug abusers, this effect can develop greater craving behavior, addiction, and relapse.
Keywords :
EDCs , Bisphenol , Paraben
Journal title :
International Journal of Medical Toxicology and Forensic Medicine
Journal title :
International Journal of Medical Toxicology and Forensic Medicine
