• Title of article

    Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus

  • Author/Authors

    Khederlou, Hamid Tehran Heart Center - Tehran University of Medical Sciences, Tehran, Iran , Rostamian, Abdolrahman Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran , Nezhadseifi, Elham Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran , Ebrahimi-louyeh, Hourvash Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran

  • Pages
    5
  • From page
    129
  • To page
    133
  • Abstract
    Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viral pneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novel coronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatory state that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertension and Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading to respiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 responded dramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective in controlling and relieving cytokine storms and related respiratory failure.
  • Farsi abstract
    فاقد چكيده فارسي
  • Keywords
    Cytokine storm , Interleukin-6 , 2019 Novel coronavirus , Respiratory failure , Systemic corticosteroid
  • Journal title
    Rheumatology Research
  • Serial Year
    2020
  • Record number

    2630158