Title of article
Transfection of Exogenous Fibroblast Growth Factor (FGF) on Human Embryonic Stem Cells (ESCs) as a Regenerative Agent for Patients with Type 1 Diabetes Mellitus (T1DM)
Author/Authors
Nolan, John Medical Faculty of Udayana University - Denpasar - Bali - Indonesia , Wijaya, Audrey Medical Faculty of Udayana University - Denpasar - Bali - Indonesia , Lianto, Agatha Medical Faculty of Udayana University - Denpasar - Bali - Indonesia , Saraswati, Made Endocrinology and Metabolism Division - Department of Internal Medicine - Medical Faculty of Udayana University/Sanglah Hospital - Denpasar - Bali - Indonesia
Pages
4
From page
11
To page
14
Abstract
Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder which results in the INS pancreatic β-cell destruction and contributes to around 5 to 10% of all diabetes mellitus cases, especially in children. At the moment, the only treatment for T1DM is by insulin injection, which is injected in order to prevent the complication of T1DM. However, several studies have shown that combination between Embryonic Stem Cells (ESCs) and the Fibroblast Growth Factor 2 (FGF-2) may be a successful modality to treat T1DM. Actually, the ESCs may become the potential therapy in treating T1DM.
Keywords
Keywords
Type 1 Diabetes Mellitus , Embryonic Stem Cells , Fibroblast Growth Factor-2
Journal title
International Journal of Medical Reviews
Serial Year
2020
Record number
2630390
Link To Document