Author/Authors :
Imam, A. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey , Karatas, C. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey , Imam, R. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey , Armutlu, A. Pathology Department - Koc University Hospital, Istanbul, Turkey , Mecit, N. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey , Karakaya, A. Radiology Department - Koc University Hospital, Istanbul, Turkey , Kalayoglu, M. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey , Kanmaz, T. Liver Transplantation Department - Koc University Hospital, Istanbul, Turkey
Abstract :
The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020—during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.
