Author/Authors :
Qaraaty, Marzieh shahed university - Traditional Medicine Clinical Trial Research Center, تهران, ايران , Kamali, Hamid shahid beheshti university of medical sciences - Faculty of Traditional Medicine - Department of Traditional Medicine, تهران, ايران , Hashem Dabaghian, Fataneh iran university of medical sciences - Research Institute for Islamic and Complementary Medicine, ايران , Zafarghandi, Nafiseh shahed university - Faculty of Medical Sciences - Departments of Obstetrics and Gynecology, تهران, ايران , Mokaberinejad, Roshanak shahid beheshti university of medical sciences - School of Traditional Medicine - Department of Traditional Medicine, تهران, ايران , Mobli, Masumeh tehran university of medical sciences tums - Faculty of Traditional Medicine - Department of Traditional Pharmacy, تهران, ايران , Amin, Gholamreza tehran university of medical sciences tums - Faculty of Traditional Medicine - Department of Traditional Pharmacy, تهران, ايران , Naseri, Mohsen shahed university - Traditional Medicine Clinical Trial Research Center, تهران, ايران , Kamalinejad, Mohammad shahid beheshti university of medical sciences - School of Pharmacy - Department of Pharmacognosy, تهران, ايران , Amin, Mohsen tehran university of medical sciences tums - Faculty of Pharmacy - Department of Drug and Food Control, تهران, ايران , Ghaseminejad, Azizeh tehran university of medical sciences tums - Department of Obstetrics and Gynecology, تهران, ايران , HosseiniKhabiri, jihan Khatam Hospital, ايران , Talei, Daryush shahed university - Medicinal Plant Research Center, تهران, ايران
Abstract :
Background: Myrtle (Myrtus communis L.) has been used in the Iranian Traditional Medicine as a treatment for abnormal uterine bleeding-menometrorrhagia. The main aim of this study is to evaluate the effect of myrtle fruit syrup on abnormal uterine bleeding-menometrorrhagia. Methods: A randomized, double-blind, placebo-controlled pilot study was conducted on 30 women suffering from abnormal uterine bleeding-menometrorrhagia. Treatment comprised of giving 15 ml oral myrtle syrup daily (5 ml three times a day) for 7 days starting from the onset of bleeding. The myrtle syrup along with placebo was repeated for 3 consecutive menstrual periods. Menstrual duration and number of used pads were recorded by the Pictorial Blood loss Assessment Chart at the end of each menstrual period. The quality of life was also evaluated using the menorrhagia questionnaire. Results: The mean number of bleeding days significantly declined from 10.6 ± 2.7 days to 8.2 ± 1.9 days after 3 months treatment with the syrup (p = 0.01) and consequently the participants in the intervention group used fewer pads after 3 months (16.4 ± 10.7) compared with the number of pads used at the beginning of the treatment (22.7 ± 12.0, p = 0.01). Bleeding days and number of pads used by the participants in the placebo group did not change significantly. Also significant changes of quality of life scores were observed in the intervention group after 3 months compared to the baseline. Conclusion: Myrtle syrup is introduced as a potential remedy for abnormal uterine bleeding- menometrorrhagia.
Keywords :
Abnormal uterine bleeding , menometrorrhagia , Effrat , e , tams , Iranian traditional medicine , Myrtus communis L , Myrtle , Myrtaceae
