Author/Authors :
Mayo, Cody Methodist Hospital - Department of Internal Medicine, USA , Kaye, Alan D. Louisiana State University - School of Medicine - Department of Pharmacology, USA , Kaye, Alan D. Louisiana State University - Health Science Center - Department of Anesthesiology, USA , Conrad, Erich Louisiana State University - Health Science Center - Department of Psychiatry, USA , Baluch, Amir University of Miami - Jackson Memorial Hospital - Department of Anesthesiology, USA , Frost, Elizabeth Mount Sinai Medical Center - Department of Anesthesiology, USA
Abstract :
Depression is diagnosed in 14 million Americans every year, and pharmacotherapy is the standard treatment. However, in approximately 50% of patients, pharmacology intervention does not resolve depression. Electroconvulsive therapy (ECT) has been a mainstay as a treatment option for treatment-resistant major depression since its inception in the 1930s. It has also been shown to be effective in treatment-resistant mania and catatonic schizophrenia. The complication rate of ECT has improved from 50% in the 1960’s to almost anecdotal adverse events, similar to the morbidity and mortality seen in minor surgery and childbirth. Although anesthetic agents are administered briefly, many patients experience significant fluctuations in physiologic parameters. The clinical anesthesiologist must be aware of these changes as well as have an understanding of perioperative pharmacological interventions. ECT is a proven therapy for select sychiatric patients, and appropriate anesthesia is a critical part of successful ECT. Careful review of the patient’s medical history may reveal pertinent anesthetic considerations.
