Pathogenesis of acne vulgaris: simplified

Acne vulgaris is a common chronic inflammatory disease of the pilosebaceous unit. It is characterized by the formation of non-inflammatory comedones and inflammatory papules, pustules, nodules and cysts. Acne is extremely common and usually starts during the teenage years but can start for the first time in their 20s and 30s. The lesions usually involve the face, back and chest. Severe inflammation may lead to scarring after healing. Psychosocial impact of acne can be tremendous and lead to a poorer quality of life. Proper understanding of pathogenesis of acne will lead to better management.