Arsenical keratoses and non-Hodgkin’s lymphoma: arsenic-induced or coincidental conditions?

Arsenic, a naturally occurring metal, is best known as a poison and can generate both acute and chronic toxicity. Exposure can occur through air, water, soil, and food. Chronic arsenic toxicity is usually asymptomatic and the first sign may be cutaneous findings. Arsenic keratosis is a precancerous lesion related to chronic arsenism. Non-Hodgkin’s lymphoma (NHL) is a T or B cell malignancy usually originating from lymph nodes and fewer in every other organ.We report a concomitant occurrence of arsenic keratosis and NHL in a Caucasian man.To our knowledge, this is the first such reported case.