PREDICTIVE VALUE OF NEUTROPHIL/LYMPHOCYTE RATIO IN PREDICTING COMPLICATIONS AFTER NON ST ELEVATION MYOCARDIAL INFARCTION

Objective: To determine the predictive value of Neutrophil to lymphocyte ratio in determining complications in patients with non ST elevation myocardial infarction. Methodology: A Cross sectional study conducted in Cardiology Unit, Hayatabad Medical Complex from August 2011 to February 2012. In a total of 250 patients with non ST elevation MI were enrolled in study. Neutrophil to lymphocyte ratio (NLR) was determined. Those with high NLR were followed over two week period to detect in hospital mortality; Atrial Fibrillation and ST segment Deviation. Association of cellular response with the incidence of post-MI mortality/complications was assessed by multiple logistic regression analyses. Results: There were 250 patients comprising of 154 (61.60%) males and 96 (38.40%) females. The overall mean age was 51.57 ±12.5 years. The frequency of high neutrophil to lymphocyte ratio was present in 78 (31.20%) patients. The In hospital mortality and atrial fibrillation rate was in 10.26% and 11.54% cases respectively while ST segment deviation was in 57.69% patients. Conclusion: Patients with Non ST Segment elevation Myocardial Infarction with high Neutrophil to lymphocyte ratio, is a good predictor of In hospital mortality, atrial fibrillation and ST segment deviation. Thus a single CBC analysis may help to identify Non- STEMI patients at risk for mortality and complications.