CLINICAL IMPORTANCE OF INTERLEUKIN-8 CONCENTRATION IN IRAQI BREAST CANCER PATIENTS

The aim of this study is to estimate the role of interleukin-8 in breast cancer Iraqi women and to assess the correlation between the serum levels of IL-8 with the progression of disease stage. Fifty patients with proved diagnosis of breast cancer by clinical examinations presented to the Al alwyah hospital for gynecological diseases and obstetrics (Breast cancer early detection clinic) in Baghdad. All were females and didn’t have received any chemo/or radiological treatment .Also, 20 samples of apparently healthy women were involved as a control. The blood samples (5ml) were drown from all of the studied cases in order to be used for measuring their serum level of IL-8 by using Enzyme–Linked Immunosorbent Assay (ELISA). The results investigated that Serum IL-8 level were increased with high significant in breast cancer patients and showed significant correlation in early disease stages compared to control group with the highest level in stage I group of patients. As a conclusion, serum level of IL-8 is highly correlated with breast cancer and might have detecting and diagnostic usefulness.