DETECTION OF SERUM TUMOR MARKERS CA15-3 AND CEA IN BREAST CANCER PATIENTS

Breast cancer is the commonest type of cancer affecting women worldwide. Different studies have dealt with the etiological factors of that cancer trying to find a way for early diagnosis and satisfactory therapy. This study is confined to the malignant subtypes invasive ductal carcinoma which, by far, the commonest type of breast cancer and invasive lobular carcinoma, designated to study the relationship between breast cancer patients and their concentrations of serum tumor markers CA15-3, CEA and correlate these concentrations with the stage of disease. The study consisted of 50 patients who were diagnosed as breast cancer patients they have attended to AL-Kadhemya Teaching Hospital (all were females) and 25control group apparently normal individuals with comparable age range of patients. The blood samples (5 ml) of venous blood was collected from all of studied cases in order to be used for immunological study by measuring their serum level of serum tumor markers CA15-3 and CEA using Enzyme-linked Immunosorbent Assay (ELISA) technique. The results have shown significant relation of CA15-3 which elevated in 46% of patients, while the serum tumor marker CEA levels were not significant which increased in 30% of patients.