Author/Authors :
Mousa, Nibal Kh. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Khadim, Labeeb A. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , kadhum, Sarab S. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Kadhum, Alaa Dh. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Sabbar, Shahad Sh. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Mohammad, Abrar N. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Ayyash, Mohammad Ab. Ministry of Science and Technology - Environmental-Water Research and Technology Directorate, Iraq , Ali, Ishrak Ab. Ministry of Health - The National Center for Drug Control and Research, Iraq
Abstract :
The study was aimed to illustrate the effect of heptachlor on seminiferous tubule and spermatic cells in the testis of mice .Heptachlor 10 mg / kg was given daily by gulping for five weeks. Mice were sacrificed after injected with colchicines in traperitonially , testis were collected after 7,21,36 days to study the effect of heptachlor on histo-testis and improved heptachlor activity not as chemical mutagen but as a tumor promoter by act directly on DNA which reflected on decreasing testicular Leydig cell and spermatogenic deficiencies when comparison with control and vitamin C.
Keywords :
Heptachlor , seminiferous tubules, histology , Leydig cell, mice.
